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4 year oldAnnouncing its first Covid-19 patient, West Virginia Governor Jim Justice said: "We knew this was coming."
New York City said it is considering a lockdown similar to one in the San Francisco Bay area.
There have so far been almost 6,000 confirmed cases of Covid-19 in the US and 105 deaths.
Globally there are about 200,000 cases and nearly 8,000 people have died.
Mayor Bill de Blasio said he would decide within two days whether to order the city's 8.5 million residents to "shelter in place".
Such a move could largely confine people to their homes, while allowing them to make necessary trips to buy groceries or medicine, walk a dog or exercise as long as they avoid public interaction.
"It's a very, very difficult decision," Mr de Blasio said. "We've never been here before. I have never heard of anything like this in the history of New York City."
Officials in the San Francisco Bay area have already ordered 6.7 million residents to stay home for all but the most crucial outings until 7 April.
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