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6 year oldScores of people are said to have been killed in an attack on the rebel-held town of Douma on Saturday.
The UK called for an urgent inquiry while Pope Francis said nothing could justify using chemical weapons.
Both Syria and Russia deny a chemical attack took place.
In a series of tweets, Mr Trump described President Assad as an "animal".
Many dead, including women and children, in mindless CHEMICAL attack in Syria. Area of atrocity is in lockdown and encircled by Syrian Army, making it completely inaccessible to outside world. President Putin, Russia and Iran are responsible for backing Animal Assad. Big price...
— Donald J. Trump (@realDonaldTrump) April 8, 2018
Read More (...)....to pay. Open area immediately for medical help and verification. Another humanitarian disaster for no reason whatsoever. SICK!
— Donald J. Trump (@realDonaldTrump) April 8, 2018
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