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4 year oldSouth Africa has announced a ban on travel from the worst-affected countries and has banned gatherings of more than 100, while Kenya has also imposed sweeping travel restrictions.
The measures are an attempt to prevent a major outbreak on a continent with poor health services.
At least 27 African states have so far been affected by the virus.
Liberia, where more than 4,800 died during the Ebola outbreak of 2014 and 2015, has become the latest African state to report a case of coronavirus.
The executive director of the state-run Environmental Protection Agency (EPA, Eugene Nagbe, tested positive after returning from Switzerland on Friday.
In total, more than 300 people have been diagnosed with the virus in Africa. Six deaths have been reported.
Most of the cases involve people arriving from Europe and North America.
But South Africa imposed the most severe restrictions on its citizens since the end of white-minority rule after reporting its first local transmission.
In an address to the nation on Sunday, President Cyril Ramaphosa declared a national disaster as the number of cases rose to 61.
"Initially, it was people who had travelled out of the country, especially from Italy, who had positively tested for the virus," he said.
"It is concerning that we are now dealing with internal transmission of the virus," Mr Ramaphosa said.
More on Africa and the virus:
Mr Ramaphosa said he would chair a government command council that would "coordinate all aspects of our extraordinary emergency response".
Among the measures he announced are:
In an address to the nation, President Uhuru Kenyatta announced:
But Kenya's efforts to tackle the global pandemic have been hampered by nurses who have started a go-slow at a coronavirus isolation ward at the Mbagathi Hospital in the capital, Nairobi.
The nurses say there is a shortage of protective gear and they have not received adequate training on how to deal with patients.
The hospital has admitted 22 people who came into contact with the first confirmed case in Kenya.
Meanwhile, a 23-year-old man has been arrested in the eastern town of Mwingi for publishing "false information", Kenya's Directorate of Criminal Investigations said in a tweet:
The man would be charged under cybercrime legislation, and risked a fine of up to $50,000 (£40,000) or a maximum prison sentence of 10 years.
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